Drug overdose deaths in the United States, 1999–2020. CDC Health Alert Network Advisory: Increase in Fatal Drug Overdoses Across the United States Driven by Synthetic Opioids Before and During the COVID-19 Pandemic.Hyattsville, MD: National Center for Health Statistics. CDCHAN-00438, 2020 Dec 14.Fentanyl is a potent synthetic opioid, which, similar to morphine, produces analgesia but to a greater extent. This robust pharmacologic agent is typically 50 to 100 times more potent. A dose of only 100 micrograms can produce equivalent analgesia to approximately 10 mg of morphine.
However, fentanyl exhibits vastly different properties and pharmacokinetics.
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